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急性后极部多灶性鳞状色素上皮病变中的脑脊液异常

Cerebrospinal fluid abnormalities in acute posterior multifocal placoid pigment epithelialopathy.

作者信息

Bullock J D, Fletcher R L

出版信息

Am J Ophthalmol. 1977 Jul;84(1):45-9. doi: 10.1016/0002-9394(77)90321-x.

DOI:10.1016/0002-9394(77)90321-x
PMID:900216
Abstract

Two patients with acute posterior multifocal placoid pigment epithelialopathy also had cerebrospinal fluid pleocytosis and elevated protein levels. A 24-year-old white women had visual acuity of counting fingers in each eye. The cerebrospinal fluid contained 56 lymphocytes per cubic millimeter and a protein level of 48 mg/100 ml. When the retinopathy resolved, visual acuity returned to R.E.: 6/60 (20/200), AND L.E.: 6/9 (20/30). A 22-year-old white man had visual acuity of counting fingers bilaterally. The initial lumbar puncture showed 70 lymphocytes and a protein level of 76 mg/100 ml. A second cerebrospinal tab showed 64 lymphocytes and a protein level of 86 mg/100 ml. Final visual acuity was R.E.: 6/15 (20/50), and L.E.: 6/6 (20/20). Neither patient received treatment for this disorder. The findings of cerebrospinal fluid cells and elevated protein levels in acute posterior multifocal placoid pigment epithelialopathy probably represent a mild viral meningitis as part of a systemic viral infection that also involves the retinal pigment epithelium or choriocapillaris.

摘要

两名急性后极部多灶性扁平色素上皮病变患者也出现了脑脊液淋巴细胞增多和蛋白水平升高。一名24岁白人女性双眼视力为眼前指数。脑脊液每立方毫米含56个淋巴细胞,蛋白水平为48mg/100ml。视网膜病变消退后,视力恢复为右眼:6/60(20/200),左眼:6/9(20/30)。一名22岁白人男性双眼视力为眼前指数。初次腰椎穿刺显示70个淋巴细胞,蛋白水平为76mg/100ml。第二次脑脊液检查显示64个淋巴细胞,蛋白水平为86mg/100ml。最终视力为右眼:6/15(20/50),左眼:6/6(20/20)。两名患者均未接受针对该疾病的治疗。急性后极部多灶性扁平色素上皮病变中脑脊液细胞及蛋白水平升高的表现可能代表轻度病毒性脑膜炎,是系统性病毒感染的一部分,该感染也累及视网膜色素上皮或脉络膜毛细血管。

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