Friedberg J
Am J Psychiatry. 1977 Sep;134(9):1010-4. doi: 10.1176/ajp.134.9.1010.
The author reviews reports of neuropathology resulting from electroconvulsive therapy in experimental animals and humans. Although findings of petechial hemorrhage, gliosis, and neuronal loss were well established in the decade following the introduction of ECT, they have been generally ignored since then. ECT produces characteristic EEG changes and severe retrograde amnesia, as well as other more subtle effects on memory and learning. The author concludes that ECT results in brain disease and questions whether doctors should offer brain damage to their patients.
作者回顾了关于实验动物和人类电休克治疗所致神经病理学的报告。尽管在电休克治疗引入后的十年里，瘀点性出血、胶质细胞增生和神经元丢失等发现已得到充分证实，但从那以后它们通常被忽视了。电休克治疗会产生特征性的脑电图变化和严重的逆行性遗忘，以及对记忆和学习的其他更细微的影响。作者得出结论，电休克治疗会导致脑部疾病，并质疑医生是否应该给患者造成脑损伤。
