Kron T, Butson M, Hunt F, Denham J
Newcastle Mater Misericordiae Hospital, Waratah, NSW, Australia.
Radiother Oncol. 1996 Nov;41(2):119-23. doi: 10.1016/s0167-8140(96)01795-1.
Prediction of skin reactions requires knowledge of the dose at various depths in the human skin. Using thermoluminescence dosimeters of three different thicknesses, the dose can be extrapolated to the surface and interpolated between the different depths. A TLD holder was designed for these TLD extrapolation measurements on patients during treatment which allowed measurements of entrance and exit skin dose with a day to day variability of +/-7% (S.D. of mean reading). In a pilot study on 18 patients undergoing breast irradiation, it was found that the angle of incidence of the radiation beam is the most significant factor influencing skin entrance dose. In most of these measurements the beam exit dose contributed 50% more to the surface dose than the entrance dose.
预测皮肤反应需要了解人体皮肤不同深度处的剂量。使用三种不同厚度的热释光剂量计，可以将剂量外推至皮肤表面，并在不同深度之间进行内插。设计了一种TLD支架，用于在治疗期间对患者进行这些TLD外推测量，该支架允许测量皮肤入射剂量和出射剂量，其每日变化率为±7%（平均读数的标准差）。在一项对18名接受乳腺放疗患者的初步研究中，发现辐射束的入射角是影响皮肤入射剂量的最重要因素。在大多数这些测量中，束流出射剂量对表面剂量的贡献比入射剂量多50%。
