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1.5T MR 直线加速器中的高分辨率入口和出口表面剂量测量。

High-resolution entry and exit surface dosimetry in a 1.5 T MR-linac.

机构信息

Centre of Medical and Radiation Physics, University of Wollongong, Wollongong, NSW, Australia.

Townsville Cancer Centre, Townsville Hospital and Health Service, Townsville, QLD, Australia.

出版信息

Phys Eng Sci Med. 2023 Jun;46(2):787-800. doi: 10.1007/s13246-023-01251-6. Epub 2023 Mar 29.

Abstract

The magnetic field of a transverse MR-linac alters electron trajectories as the photon beam transits through materials, causing lower doses at flat entry surfaces and increased doses at flat beam-exiting surfaces. This study investigated the response of a MOSFET detector, known as the MOSkin™, for high-resolution surface and near-surface percentage depth dose measurements on an Elekta Unity. Simulations with Geant4 and the Monaco treatment planning system (TPS), and EBT-3 film measurements, were also performed for comparison. Measured MOSkin™ entry surface doses, relative to D, were (9.9 ± 0.2)%, (10.1 ± 0.3)%, (11.3 ± 0.6)%, (12.9 ± 1.0)%, and (13.4 ± 1.0)% for 1 × 1 cm, 3 × 3 cm, 5 × 5 cm, 10 × 10 cm, and 22 × 22 cm fields, respectively. For the investigated fields, the maximum percent differences of Geant4, TPS, and film doses extrapolated and interpolated to a depth suitable for skin dose assessment at the beam entry, relative to MOSkin™ measurements at an equivalent depth were 1.0%, 2.8%, and 14.3%, respectively, and at a WED of 199.67 mm at the beam exit, 3.2%, 3.7% and 5.7%, respectively. The largest measured increase in exit dose, due to the electron return effect, was 15.4% for the 10 × 10 cm field size using the MOSkin™ and 17.9% for the 22 × 22 cm field size, using Geant4 calculations. The results presented in the study validate the suitability of the MOSkin™ detector for transverse MR-linac surface dosimetry.

摘要

横向磁共振直线加速器的磁场会改变光子束穿过材料时的电子轨迹,从而导致在平坦的入射表面剂量较低,在平坦的出射表面剂量增加。本研究调查了 MOSFET 探测器(称为 MOSkin™)在 Elekta Unity 上进行高分辨率表面和近表面百分深度剂量测量的响应。还进行了 Geant4 和 Monaco 治疗计划系统(TPS)的模拟以及 EBT-3 胶片测量,以便进行比较。测量的 MOSkin™ 入射表面剂量与 D 的比值分别为(9.9 ± 0.2)%、(10.1 ± 0.3)%、(11.3 ± 0.6)%、(12.9 ± 1.0)%和(13.4 ± 1.0)%,用于 1×1cm、3×3cm、5×5cm、10×10cm 和 22×22cm 射野。对于所研究的射野,最大的差异百分比为 1.0%、2.8%和 14.3%,相对于 MOSkin™ 在等效深度处的测量值,Geant4、TPS 和胶片剂量外推和内插到适合于评估皮肤剂量的深度,分别在束出口处的 WED 为 199.67mm 时,分别为 3.2%、3.7%和 5.7%。由于电子返回效应,出口剂量最大的测量增加量为 10×10cm 射野大小的 15.4%,使用 MOSkin™ 和 22×22cm 射野大小的 17.9%,使用 Geant4 计算。本研究中呈现的结果验证了 MOSkin™ 探测器用于横向磁共振直线加速器表面剂量测量的适用性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3066/10209272/fbe19fb02f07/13246_2023_1251_Fig1_HTML.jpg

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