色胺和β-咔啉系列碱的化学性质及生物活性
Chemistry and biological activity of a tryptamine and beta-carboline series of bases.
作者信息
Begum S, Usmani S B, Siddiqui B S, Saeed S A, Farnaz S, Khan K A, Khan S A, Khalid S M, Zia A
机构信息
H.E.J. Research Institute of Chemistry, University of Karachi, Pakistan.
出版信息
Arzneimittelforschung. 1996 Dec;46(12):1163-8.
PMID:9006793
Abstract
Twenty-six derivatives of harmaline and tetrahydroharmine were prepared and characterized by UV, IR, MS, and NMR spectroscopy. They were tested for their antimicrobial, antiplatelet aggregation and cytotoxic activity. Their effect on central nervous system was also studied.
摘要
制备了26种哈尔满和四氢哈尔满的衍生物，并通过紫外光谱、红外光谱、质谱和核磁共振光谱对其进行了表征。对它们进行了抗菌、抗血小板聚集和细胞毒性活性测试。还研究了它们对中枢神经系统的影响。
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