Janetschke P, Günther H, Kielstein P, Martin J, Schönherr W
Arch Exp Veterinarmed. 1977;31(2):289-98.
Bordetella have been frequently detectable from lesioned lung material of swine as well as from the upper respiratory tracts of clinically intact animals. Pneumonia, different in extent, was produced in primarily specific pathogen free pigs by intratracheal and intranasal application of eight Bordetella isolates. Moderate to medium manifestations of focal pneumonia with scattered speckles developed, with severity depending on dosage and mode of infection. Histologically, they were characterised by vascular lesions and fibroblastic proliferation. This type of pneumonia thus was differentiated by the above characteristics from pneumonia caused by heamophils and Pasteurellae. Under conditions of natural exposure, Bordetella pneumonia can be expected to develop primarily due to defective host-patasite relationship. Bordetellae, in this context, are considered only conditionally pathogenic. Bordetellal infection will have to be taken into consideration in differential diagnosis whenever checks are made on pigs in industrialised units.
从猪的病变肺部材料以及临床健康动物的上呼吸道中经常可检测到博德特氏菌。通过气管内和鼻内接种8株博德特氏菌分离株，在原本无特定病原体的猪中引发了程度不同的肺炎。出现了伴有散在斑点的局灶性肺炎的中度至中等表现，其严重程度取决于剂量和感染方式。组织学上，其特征为血管病变和成纤维细胞增殖。因此，这种类型的肺炎通过上述特征与由嗜血杆菌和巴氏杆菌引起的肺炎相区分。在自然暴露条件下，博德特氏菌肺炎预计主要由于宿主与病原体关系缺陷而发生。在这种情况下，博德特氏菌仅被视为条件致病菌。在对工业化养殖场的猪进行检查时，无论何时进行鉴别诊断，都必须考虑博德特氏菌感染。
