Torrey E F, Torrey B B, Peterson M R
Arch Gen Psychiatry. 1977 Sep;34(9):1065-70. doi: 10.1001/archpsyc.1977.01770210079007.
The birth months of persons later diagnosed as schizophrenic were studied. Data were collected from 19 states on 53,584 schizophrenics born between 1920 and 1955. The controls were the general births in the same states for the same years. A highly significant peak in schizophrenic births was found from December to May, most marked in March and April. The seasonality was stronger in New England and the Midwest than in the South. Previous studies of schizophrenic births are also reviewed. The cumulative evidence would appear to establish more firmly a winter and spring seasonality of schizophrenic births in northern Europe and the eastern United States. Selection of patients, nutritional factors, environmental factors, genetic factors, and infectious agents are discussed as possible etiological explanations.
对后来被诊断为精神分裂症患者的出生月份进行了研究。收集了来自19个州的1920年至1955年间出生的53584名精神分裂症患者的数据。对照组为同一年这些州的普通出生人口。发现精神分裂症患者出生的高峰期出现在12月至次年5月，3月和4月最为明显。新英格兰和中西部地区的季节性比南部地区更强。还回顾了之前关于精神分裂症患者出生情况的研究。累积证据似乎更有力地证实了北欧和美国东部精神分裂症患者出生存在冬春季节性。讨论了患者选择、营养因素、环境因素、遗传因素和传染因子作为可能的病因解释。
