耳萝卜螺（软体动物，肺螺亚纲）发育中的神经系统中FMRF酰胺样免疫反应性的瞬时和持续表达。

Transient and sustained expression of FMRFamide-like immunoreactivity in the developing nervous system of Lymnaea stagnalis (Mollusca, Pulmonata).

Voronezhskaya E E, Elekes K

Balaton Limnological Research Institute, Hungarian Academy of Sciences, Tihany, Hungary.

Cell Mol Neurobiol. 1996 Dec;16(6):661-76. doi: 10.1007/BF02151903.

Abstract

In the present study we have investigated the ontogeny of FMRFamide expression in the snail, Lymnaea stagnalis, from its first appearance to its distribution in young adults. 2. The first FMRFamide-like immunoreactive (FaLI) cells within CNS appear by E45 embryonic stage (premetamorphic veliger). The number of FaLI neurons increases throughout both pre- and post-hatching development. 3. Both transient and sustained expression of FMRFamide-like immunoreactivity by specific sets of neurons occurs. Two cells which transiently express immunoreactivity appear outside the future CNS by the stage E45. Other population of transient FaLI neurons includes bilaterally symmetric groups of cells in the cerebral and pedal ganglia during posthatching stages P1 (hatchlings) to P5 (juveniles). All other immunostained cells which appear during development maintain their transmitter phenotype into adulthood. 4. The possible role of FMRFamide-related peptides in the processes of morpho- and neurogenesis is discussed.

摘要

在本研究中，我们调查了福寿螺中FMRF酰胺表达的个体发生过程，从其首次出现到在年轻成体中的分布情况。2. 中枢神经系统内首个FMRF酰胺样免疫反应性（FaLI）细胞在胚胎发育第45阶段（前变态面盘幼虫）出现。在孵化前和孵化后的整个发育过程中，FaLI神经元的数量都在增加。3. 特定神经元组会出现FMRF酰胺样免疫反应性的瞬时表达和持续表达。在胚胎发育第45阶段，两个瞬时表达免疫反应性的细胞出现在未来的中枢神经系统之外。其他瞬时FaLI神经元群体包括孵化后阶段P1（幼体）到P5（幼年期）时，脑和足神经节中两侧对称的细胞群。发育过程中出现的所有其他免疫染色细胞在成年期都保持其递质表型。4. 讨论了FMRF酰胺相关肽在形态发生和神经发生过程中的可能作用。