Waters J C, Salmon E
Department of Biology, University of North Carolina, Chapel Hill, NC 27599-3280, USA.
Curr Opin Cell Biol. 1997 Feb;9(1):37-43. doi: 10.1016/s0955-0674(97)80149-4.
Recent studies have revealed that, in some systems, chromatin has the ability to stabilize microtubules and organize them into bipolar spindles independently of kinetochores and centrosomes. In addition, several molecules have been identified recently that are necessary for spindle assembly; these include proteins that regulate microtubule dynamics, proteins that organize microtubule minus ends into spindle poles, and members of the kinesin superfamily that reside on the chromosome arms.
最近的研究表明，在某些体系中，染色质能够稳定微管并将它们独立于动粒和中心体组织成双极纺锤体。此外，最近已鉴定出几种对于纺锤体组装必不可少的分子；这些分子包括调节微管动力学的蛋白质、将微管负端组织成纺锤体极的蛋白质以及位于染色体臂上的驱动蛋白超家族成员。
