Reddy M V, Harper M K, Faulkner D J
Scripps Institution of Oceanography, University of California at San Diego, La Jolla 92093-0212, USA.
J Nat Prod. 1997 Jan;60(1):41-3. doi: 10.1021/np9606207.
The Palauan sponge Luffariella sp. contained manoalide (6) and secomanoalide (7) as the major metabolites. The minor metabolites, luffasterols A-C (3-5) are 9,11-secosterols that contain a 3 beta-acetoxy-5 alpha,6 alpha-epoxy-9-oxo-9,11-secocholest-7-en-11-al ring system joined to three different side chains. The structures of the luffasterols were elucidated by interpretation of spectroscopic data.
