Ferguson A
Department of Medicine, University of Edinburgh.
Immunology. 1996 Dec;89(4):475-82. doi: 10.1046/j.1365-2567.1996.d01-791.x.
This paper, written by the President of the Society for Mucosal Immunology, marks the 9th International Congress of Mucosal Immunology, in Sydney: Mucosal Solutions. Current molecular, cellular and animal work in mucosal immunity has great potential when applied to issues of human and animal health. However, practical and technical problems in the transfer of theoretical concepts into clinically based research must not be underestimated. Ideally, studies in disease need to be designed and run jointly by clinicians and scientists, as illustrated by examples drawn from Crohn's disease. Ethical aspects of research in mucosal physiology and disease are challenging, but not insurmountable.
本文由黏膜免疫学会主席撰写,纪念在悉尼召开的第九届黏膜免疫国际大会:黏膜解决方案。目前黏膜免疫领域的分子、细胞及动物研究成果在应用于人类和动物健康问题时具有巨大潜力。然而,将理论概念转化为临床研究过程中存在的实际和技术问题绝不可被低估。理想情况下,疾病研究应由临床医生和科学家共同设计并开展,克罗恩病的相关实例就说明了这一点。黏膜生理学及疾病研究中的伦理问题颇具挑战性,但并非无法克服。