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Nucleic Acids Res. 1997 Jan 1;25(1):138. doi: 10.1093/nar/25.1.138.
2
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The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis.TP53 网站：TP53 突变数据库和 TP53 突变分析的综合资源中心。
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本文引用的文献

1
APC mutations in colorectal tumors with mismatch repair deficiency.错配修复缺陷的结直肠肿瘤中的APC突变
Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9049-54. doi: 10.1073/pnas.93.17.9049.
2
Deletions and insertions in the p53 tumor suppressor gene in human cancers: confirmation of the DNA polymerase slippage/misalignment model.人类癌症中p53肿瘤抑制基因的缺失和插入：DNA聚合酶滑动/错配模型的证实
Cancer Res. 1996 May 1;56(9):2130-6.
3
p53 gene mutation: software and database.p53基因突变：软件与数据库
Nucleic Acids Res. 1996 Jan 1;24(1):147-50. doi: 10.1093/nar/24.1.147.
4
Software and database for the analysis of mutations in the human FBN1 gene.用于分析人类FBN1基因突变的软件和数据库。
Nucleic Acids Res. 1996 Jan 1;24(1):137-40. doi: 10.1093/nar/24.1.137.
5
APC gene: database of germline and somatic mutations in human tumors and cell lines.APC基因：人类肿瘤和细胞系中种系及体细胞突变数据库。
Nucleic Acids Res. 1996 Jan 1;24(1):121-4. doi: 10.1093/nar/24.1.121.
6
Familial adenomatous polyposis: desmoid tumours and lack of ophthalmic lesions (CHRPE) associated with APC mutations beyond codon 1444.家族性腺瘤性息肉病：与密码子1444以外的APC突变相关的硬纤维瘤和无眼病变（先天性视网膜色素上皮肥厚）
Hum Mol Genet. 1995 Mar;4(3):337-40. doi: 10.1093/hmg/4.3.337.
7
Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene.APC基因特定区域发生突变的家族中的重度加德纳综合征。
Am J Hum Genet. 1995 Nov;57(5):1151-8.

p53与APC基因突变：软件与数据库

p53 and APC gene mutations: software and databases.

作者信息

Béroud C, Soussi T

机构信息

Hôpital Necker Enfants Malades, U383 INSERM, Paris, France.

出版信息

Nucleic Acids Res. 1997 Jan 1;25(1):138. doi: 10.1093/nar/25.1.138.

DOI:10.1093/nar/25.1.138
PMID:9016523
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC146392/
Abstract

A large number of different mutations in the APC and p53 tumor suppressor genes have been identified in various types of cancer. This substantial increase since our previous reports can enable analyses which were not previously possible. In order to capture all these new data, the software permitting analysis has been improved. This report describes the various improvements since the second release of the database.

摘要

在各类癌症中已鉴定出大量存在于APC和p53肿瘤抑制基因中的不同突变。自我们之前的报告以来，这一显著增加使得此前无法进行的分析成为可能。为了获取所有这些新数据，允许进行分析的软件已得到改进。本报告描述了自数据库第二次发布以来的各种改进情况。