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p53与APC基因突变:软件与数据库

p53 and APC gene mutations: software and databases.

作者信息

Béroud C, Soussi T

机构信息

Hôpital Necker Enfants Malades, U383 INSERM, Paris, France.

出版信息

Nucleic Acids Res. 1997 Jan 1;25(1):138. doi: 10.1093/nar/25.1.138.

Abstract

A large number of different mutations in the APC and p53 tumor suppressor genes have been identified in various types of cancer. This substantial increase since our previous reports can enable analyses which were not previously possible. In order to capture all these new data, the software permitting analysis has been improved. This report describes the various improvements since the second release of the database.

摘要

在各类癌症中已鉴定出大量存在于APC和p53肿瘤抑制基因中的不同突变。自我们之前的报告以来,这一显著增加使得此前无法进行的分析成为可能。为了获取所有这些新数据,允许进行分析的软件已得到改进。本报告描述了自数据库第二次发布以来的各种改进情况。

相似文献

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p53 and APC gene mutations: software and databases.p53与APC基因突变:软件与数据库
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p53 gene mutation: software and database.p53基因突变:软件与数据库
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本文引用的文献

1
APC mutations in colorectal tumors with mismatch repair deficiency.错配修复缺陷的结直肠肿瘤中的APC突变
Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9049-54. doi: 10.1073/pnas.93.17.9049.
3
p53 gene mutation: software and database.p53基因突变:软件与数据库
Nucleic Acids Res. 1996 Jan 1;24(1):147-50. doi: 10.1093/nar/24.1.147.

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