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组蛋白及组蛋白折叠序列与结构:一个数据库。

Histone and histone fold sequences and structures: a database.

作者信息

Baxevanis A D, Landsman D

机构信息

Genome Technology Branch, National Center for Human Genome Research, National Institutes of Health, Bethesda, MD 20892, USA.

出版信息

Nucleic Acids Res. 1997 Jan 1;25(1):272-3. doi: 10.1093/nar/25.1.272.

Abstract

A database of aligned histone protein sequences has been constructed based on the results of homology searches of the major public sequence databases. In addition, sequences of proteins identified as containing the histone fold motif and structures of all known histone and histone fold proteins have been included in the current release. Database resources include information on conflicts between similar sequence entries in different source databases, multiple sequence alignments, and links to the Entrez integrated information retrieval system at the National Center for Biotechnology Information (NCBI). The database currently contains over 1000 protein sequences. All sequences and alignments in this database are available through the World Wide Web at: http: //www.ncbi.nlm.nih.gov/Baxevani/HISTONES/ .

摘要

基于对主要公共序列数据库的同源性搜索结果,构建了一个比对后的组蛋白序列数据库。此外,当前版本还纳入了被鉴定为含有组蛋白折叠基序的蛋白质序列以及所有已知组蛋白和组蛋白折叠蛋白的结构。数据库资源包括不同源数据库中相似序列条目的冲突信息、多序列比对以及与美国国立医学图书馆国家生物技术信息中心(NCBI)的Entrez综合信息检索系统的链接。该数据库目前包含1000多条蛋白质序列。此数据库中的所有序列和比对信息均可通过万维网获取,网址为:http://www.ncbi.nlm.nih.gov/Baxevani/HISTONES/

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