Tuomainen A, Kangas J, Liesivuori J, Manninen A
Finnish Institute of Occupational Health, Kuopio, Finland.
Int Arch Occup Environ Health. 1996;69(1):62-4. doi: 10.1007/BF02630740.
This study examined the possibility of using biological monitoring to assess deltamethrin exposure among greenhouse workers. The synthetic pyrethroid deltamethrin was sprayed in five greenhouses by cold for generators, and the exposure was biologically monitored by analysing the concentration of its metabolite, 3-phenoxybenzoic acid, by a gas chromato-graphic method after derivatization with pentafluorobenzyl bromide. 3-Phenoxybenzoic acid was found in the urine of two of the ten workers studied. The urine concentration of the metabolite varied from 2.4 to 51.7 micrograms/l. These results show that 3-phenoxybenzoic acid is suitable for biological monitoring for the assessment of exposure to deltamethrin.
本研究探讨了使用生物监测评估温室工人溴氰菊酯暴露情况的可能性。用冷雾发生器在五个温室中喷洒了合成拟除虫菊酯溴氰菊酯,并通过气相色谱法,在用五氟苄基溴衍生化后分析其代谢物3-苯氧基苯甲酸的浓度,对暴露情况进行生物监测。在所研究的10名工人中,有两人的尿液中发现了3-苯氧基苯甲酸。该代谢物的尿液浓度在2.4至51.7微克/升之间变化。这些结果表明,3-苯氧基苯甲酸适用于生物监测以评估溴氰菊酯暴露情况。