Plasma metoprolol concentrations in young, old and hypertensive subjects.
作者信息
Kendall M J, Brown D, Yates R A
出版信息
Br J Clin Pharmacol. 1977 Aug;4(4):497-9.
Abstract
摘要
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Plasma metoprolol concentrations in young, old and hypertensive subjects.年轻、老年和高血压受试者的血浆美托洛尔浓度。
Br J Clin Pharmacol. 1977 Aug;4(4):497-9.
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Pharmacokinetics of metoprolol and its metabolite alpha-OH-metoprolol in healthy, non-smoking, elderly individuals.美托洛尔及其代谢产物α-羟基美托洛尔在健康、不吸烟老年个体中的药代动力学。
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Lack of evidence for polymorphism in metoprolol metabolism.美托洛尔代谢中缺乏多态性的证据。
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Metoprolol in the aged hypertensive: a comparison of two dosage schedules.美托洛尔用于老年高血压患者：两种给药方案的比较。
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本文引用的文献
1
Effect of age and sex on human drug metabolism.年龄和性别对人体药物代谢的影响。
Br Med J. 1971 Sep 11;3(5775):607-9. doi: 10.1136/bmj.3.5775.607.
2
Pharmacokinetics of oral propranolol in chronic renal disease.慢性肾病患者口服普萘洛尔的药代动力学
Clin Pharmacol Ther. 1974 Nov;16(5 Part 1):761-9. doi: 10.1002/cpt1974165part1761.
3
The effect of age on plasma levels of propranolol and practolol in man.年龄对人体血浆中普萘洛尔和醋氨心安水平的影响。
Br J Clin Pharmacol. 1975 Aug;2(4):303-6. doi: 10.1111/j.1365-2125.1975.tb02774.x.
4
Metabolism of metoprolol-(3-h) in man, the dog and the rat.美托洛尔 -（3 - H）在人、狗和大鼠体内的代谢。
Acta Pharmacol Toxicol (Copenh). 1975;36(Suppl 5):125-35. doi: 10.1111/j.1600-0773.1975.tb03329.x.
5
Plasma levels and effects of metoprolol on blood pressure and heart rate in hypertensive patients after an acute dose and between two doses during long-term treatment.急性给药后及长期治疗期间两剂之间美托洛尔在高血压患者中的血浆水平及其对血压和心率的影响。
Clin Pharmacol Ther. 1975 Apr;17(4):400-8. doi: 10.1002/cpt1975174400.
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