Ceha L J, Presperin C, Young E, Allswede M, Erickson T
Cook County Hospital Department of Emergency Medicine, University of Illinois College of Pharmacy, Chicago, USA.
J Emerg Med. 1997 Jan-Feb;15(1):65-9. doi: 10.1016/s0736-4679(96)00244-2.
The woody nightshade, Solanum dulcamara, belongs to the genus Solanum and its primary toxin is solanine. We report a large nightshade ingestion in a 4-yr-old girl who presented to the emergency department in acute anticholinergic crisis. The child was given 0.2 mg of intravenous physostigmine (0.02 mg/kg). Within 50 min, the patient received two additional equal doses with complete resolution of symptoms. After 36 h of observation, the child was discharged. Our patient presented with symptoms more suggestive of the deadly nightshade species, Atropa belladonna, which is native to Europe; however, a detailed laboratory analysis of the suspect berries revealed no atropine or hyoscyamine. Analysis did reveal sterols consistent with solanine. This is a unique case presentation of woody nightshade, S. dulcamara, poisoning presenting with anticholinergic crisis and responding to physostigmine.
木本茄属植物龙葵属于茄属，其主要毒素是茄碱。我们报告了一名4岁女孩大量摄入龙葵的病例，她因急性抗胆碱能危象被送往急诊科。该患儿静脉注射了0.2毫克毒扁豆碱（0.02毫克/千克）。在50分钟内，患者又接受了两次等量剂量的药物，症状完全缓解。经过36小时的观察，患儿出院。我们的患者表现出的症状更像是原产于欧洲的致命茄属植物颠茄；然而，对可疑浆果的详细实验室分析未发现阿托品或莨菪碱。分析确实发现了与茄碱一致的固醇。这是一例独特的木本茄属植物龙葵中毒病例，表现为抗胆碱能危象并对毒扁豆碱有反应。
