Sreedharan A, Jayshree R S, Sridhar H
Department of Microbiology, Kidwai Memorial Institute of Oncology, Bangalore, India.
J Diarrhoeal Dis Res. 1996 Sep;14(3):211-3.
The incidence of cryptosporidiosis was studied in 560 cancer patients presenting with symptoms of diarrhoea. Cryptosporidium oocysts were detected in the stool specimens by modified acid fast staining. Blood was examined for HIV antibodies from patients whose stool specimens were positive for Cryptosporidium oocysts. Oocysts were detected in 7 of the 560 (1.3%) patients who were receiving chemotherapy and had diarrhoea; in five of them the symptoms were acute, while tow patients had chronic diarrhoea. Of these seven patients, five had cancer of haemopoetic system, one had cancer of cervix and one had uterine sarcoma. None of the patients positive for oocysts were positive for HIV antibodies, ruling out the possibility of an opportunistic infection due to HIV infection.
对560例出现腹泻症状的癌症患者隐孢子虫病的发病率进行了研究。通过改良抗酸染色法在粪便标本中检测隐孢子虫卵囊。对粪便标本中隐孢子虫卵囊呈阳性的患者检测血液中的HIV抗体。在560例接受化疗且有腹泻症状的患者中,有7例(1.3%)检测到卵囊;其中5例症状为急性,2例为慢性腹泻。这7例患者中,5例患有造血系统癌症,1例患有宫颈癌,1例患有子宫肉瘤。卵囊呈阳性的患者均未检测出HIV抗体呈阳性,排除了因HIV感染导致机会性感染的可能性。