Telischi M, Patel A R, Zafar M, Hoiberg R
Blood. 1977 Oct;50(4):743-8.
Since microaggregates have been implicated in posttransfusion pulmonary insufficiency, their elimination has become an active concern in blood transfusion. Various types of filters, as well as frozen-preserved erythrocytes, have been used to provide blood relatively low in microaggregates. We have counted particles in frozen-stored blood before deglycerolization, after washing in each of three cell processing systems, and after filtration through a 40-micrometer filter. Washing frozen erythrocytes reduced the total particle counts by an average of 89%. Slight differences were found among the three blood processors with respect to particle removal. Passing washed blood through a 40-micrometer filter did not result in significant further reduction in particle counts. Hence, the use of such filters in a frozen-preserved blood system is not warranted.
由于微聚体与输血后肺功能不全有关，其清除已成为输血领域一个备受关注的问题。各种类型的过滤器以及冷冻保存的红细胞已被用于提供微聚体含量相对较低的血液。我们对冷冻保存的血液在去甘油化前、在三种细胞处理系统中分别洗涤后以及通过40微米过滤器过滤后进行了颗粒计数。洗涤冷冻红细胞平均使总颗粒数减少了89%。在三种血液处理设备之间，在颗粒清除方面发现了细微差异。让洗涤后的血液通过40微米过滤器并没有导致颗粒数进一步显著减少。因此，在冷冻保存血液系统中使用此类过滤器并无必要。
