Rojas-Poceros G, Viveros-Rentería E, Fernández-Castro E, Esparza-Iturbide J A, Cabra-Zurita R, Kably-Ambe A
Servicio de Ginecología y Obstetricia, American British Cowdray Hospital, México, D.F.
Ginecol Obstet Mex. 1996 Dec;64:523-7.
A descriptive, transversal retrospective study was performed, to determine the prevalence of HELLP syndrome among patients with Pregnancy-Induced Hypertension (PIH), who were admitted into the Gynecology and Obstetrics Service the American British Cowdray Hospital in Mexico City, since July 1992 to June 1995. We detected a total or 11 patients who had the diagnostic parameters proposed by Sibaí, those were 11.8% of all the patients with PIH. The medial gestational age was 33 weeks (range from 30 to 39) The mean tensional levels were 170/ 107 mm Hg, in base of platelet count, nine patients were classified as Class I (82%) and two in Class II (18%), the medial peak levels of transaminases and bilirubins was reached 40 hours and that of lactic deshidrogenase 60 hours after the diagnosis was established, while the minimum levels of hematocrit and platelets were at 48 and 57 respectively. The mean weight of the neonates was 1,655 g, the maternal mortality rate was 9% and the perinatal 8.3%, the diagnosis of HELLP syndrome was established before delivery in 40% of the cases and after that in 60%, puerperal HELLP may occur more frequently that is believed. Point out the importance of early detection of this clinic entity in order to establish an opportune and efficient treatment which improves maternal and fetal prognosis.
进行了一项描述性横断面回顾性研究，以确定1992年7月至1995年6月期间入住墨西哥城美国英国考德雷医院妇产科的妊娠高血压（PIH）患者中HELLP综合征的患病率。我们共检测出11例符合西拜提出的诊断参数的患者，占所有PIH患者的11.8%。平均孕周为33周（范围30至39周）。平均血压水平为170/107mmHg，根据血小板计数，9例患者被归类为I级（82%），2例为II级（18%）。诊断确立后，转氨酶和胆红素的平均峰值水平在40小时达到，乳酸脱氢酶在诊断确立后60小时达到，而血细胞比容和血小板的最低水平分别在48小时和57小时出现。新生儿平均体重为1655g，孕产妇死亡率为9%，围产儿死亡率为8.3%。40%的病例在分娩前确诊为HELLP综合征，60%在分娩后确诊。产后HELLP综合征的发生率可能比人们认为的更高。指出早期发现这一临床实体对于建立恰当有效的治疗以改善母婴预后的重要性。
