Naville D, Jaillard C, Barjhoux L, Durand P, Bégeot M
INSERM-INRA U418, Hôpital Debrousse, Lyon, France.
Biochem Biophys Res Commun. 1997 Jan 3;230(1):7-12. doi: 10.1006/bbrc.1996.5911.
One kb of the 5'-flanking region of the human ACTH receptor gene was isolated and partially characterized. Transient transfections with hGH reporter confirmed the promoter activity in Y1 cells. Putative elements for transcription factors involved in regulation were noted in the sequence. The promoter activity of some of the constructs is responsive to a treatment by forskolin, due to the presence of several CRE-like sequences.
