Makuuchi H, Tanaka H, Shimada H, Chino O, Nishi T, Machimura T, Nakasaki H, Mitomi T
Dept. of Surgery II, Tokai University School of Medicine, Isehara, Japan.
Gan To Kagaku Ryoho. 1997 Jan;24(1):1-7.
Two hundred eleven cases, 27.1%, of multiple primary cancers of esophagus and other organs were found in 778 cases of esophageal cancers which were treated in our institution. Among them, double cancer accounted for 92.9%, triple cancer accounted for 6.6% and quadruple cancer for 0.5%. As for the other organ of esophageal double cancer. 59.9% of them were head and neck, 25.1% were stomach, 4.9% were colon and rectum, and remaining included liver, breast, lymphoma lung kidney etc. Head and neck cancers consisted with hypopharynx, tongue, larynx, oral floor and gingiva regarding incidence in its order. For discovering of double cancer in esophagus and other organs, 1. head and neck, stomach, colon and rectum, lung, liver etc. should be investigated preoperatively in the patients of esophageal cancer, 2. Esophagus should be examined preoperatively in the patients of these cancers, 3. Screening of esophageal cancer should be performed in the patients of high risks of esophageal cancer. As for the multiple primary cancer of esophagus and other organs, the balance of treatment should be considered to take the priority of the cancer limiting the prognosis.
在我院接受治疗的778例食管癌患者中，发现211例（占27.1%）患有食管癌与其他器官的多原发性癌。其中，双癌占92.9%，三癌占6.6%，四癌占0.5%。至于食管癌双癌的其他器官，其中59.9%为头颈部，25.1%为胃，4.9%为结肠和直肠，其余包括肝、乳腺、淋巴瘤、肺、肾等。头颈部癌按发病率依次包括下咽、舌、喉、口底和牙龈。为发现食管癌与其他器官的双癌，1. 食管癌患者术前应对头颈部、胃、结肠和直肠、肺、肝等进行检查；2. 这些癌症患者术前应检查食管；3. 食管癌高危患者应进行食管癌筛查。至于食管癌与其他器官的多原发性癌，应考虑治疗的平衡，优先治疗限制预后的癌症。
