Galtier N, Gouy M, Gautier C
CNRS UMR 5558, Biométrie, Génétique et Biologie des Populations, Université Claude Bernard Lyon, Villeurbanne, France.
Comput Appl Biosci. 1996 Dec;12(6):543-8. doi: 10.1093/bioinformatics/12.6.543.
SEAVIEW and PHYLO_WIN are two graphic tools for X Windows-Unix computers dedicated to sequence alignment and molecular phylogenetics. SEAVIEW is a sequence alignment editor allowing manual or automatic alignment through an interface with CLUSTALW program. Alignment of large sequences with extensive length differences is made easier by a dot-plot-based routine. The PHYLO_WIN program allows phylogenetic tree building according to most usual methods (neighbor joining with numerous distance estimates, maximum parsimony, maximum likelihood), and a bootstrap analysis with any of them. Reconstructed trees can be drawn, edited, printed, stored, evaluated according to numerous criteria. Taxonomic species groups and sets of conserved regions can be defined by mouse and stored into sequence files, thus avoiding multiple data files. Both tools are entirely mouse driven. On-line help makes them easy to use. They are freely available by anonymous ftp at biom3.univ-lyon1.fr/pub/ mol_phylogeny or http:@acnuc.univ-lyon1.fr/, or by e-mail to galtier@biomserv.univ-lyon1.fr.
SEAVIEW和PHYLO_WIN是两款适用于X Windows - Unix计算机的图形工具，专门用于序列比对和分子系统发育分析。SEAVIEW是一个序列比对编辑器，可通过与CLUSTALW程序的接口进行手动或自动比对。基于点阵图的程序使比对长度差异较大的大序列变得更容易。PHYLO_WIN程序允许根据最常用的方法（带有多种距离估计的邻接法、最大简约法、最大似然法）构建系统发育树，并对其中任何一种方法进行自展分析。重建的树可以根据众多标准进行绘制、编辑、打印、存储和评估。分类物种组和保守区域集可以通过鼠标定义并存储到序列文件中，从而避免多个数据文件。这两款工具完全由鼠标驱动。在线帮助使它们易于使用。可通过匿名ftp在biom3.univ-lyon1.fr/pub/mol_phylogeny或http:@acnuc.univ-lyon1.fr/获取，也可通过电子邮件发送至galtier@biomserv.univ-lyon1.fr免费获得。
