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细胞数量与细胞大小:大鼠器官的生长发育及追赶生长的调控

Cell number and cell size: organ growth and development and the control of catch-up growth in rats.

作者信息

Sands J, Dobbing J, Gratrix C A

出版信息

Lancet. 1979 Sep 8;2(8141):503-5. doi: 10.1016/s0140-6736(79)91556-3.

DOI:10.1016/s0140-6736(79)91556-3
PMID:90220
Abstract

One of the most important hypotheses for the control of catch-up after nutritional growth restriction relates developmental vulnerability to an early phase of cell multiplication, rather than to a later phase of growth of cell size. A re-examination of growing tissues, however, does not show the expected sequence of growth events, and the former hypothesis is therefore not supported.

摘要

关于营养性生长受限后追赶生长控制的最重要假说之一认为,发育易损性与细胞增殖的早期阶段有关,而非与细胞大小生长的后期阶段有关。然而,对生长组织的重新检查并未显示出预期的生长事件顺序,因此前一种假说不成立。

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Cell number and cell size: organ growth and development and the control of catch-up growth in rats.细胞数量与细胞大小:大鼠器官的生长发育及追赶生长的调控
Lancet. 1979 Sep 8;2(8141):503-5. doi: 10.1016/s0140-6736(79)91556-3.
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Cell size and cell number: a reconsideration of organ growth and catch-up potential.细胞大小与细胞数量:对器官生长及追赶潜能的重新思考。
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Cell size and cell number in tissue growth and development. An old hypothesis reconsidered.组织生长与发育中的细胞大小和细胞数量。重新审视一个古老的假说。
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