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干燥综合征合并胸腺瘤

[Sjögren's syndrome complicated by thymoma].

作者信息

Terashima M, Nishimura Y, Kageshita T, Kajiura Y, Nakata H, Matsubara M, Iwai Y, Yokoyama M

机构信息

Department of Respiratory Disease, Takatsuki General Hospital, Osaka, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1996 Dec;34(12):1369-74.

PMID:9022322
Abstract

A 43-year-old woman with a history of Sjögren's syndrome was admitted to our hospital because of dyspnea due to anemia. Her chest X ray film on admission revealed an anterior mediastinal tumor. We diagnosed this tumor as a thymoma based on a chest CT scan and magnetic resonance imaging. Because the latter indicated that the thymoma may have involved the mediastinal great vessels, preoperative chemotherapy with cisplatin, doxorubicin hydrochloride, vincristine sulfate and cyclophosphamide. Thereafter the tumor was successfully resected along with part of the right pleura. Thymoma as a complication of Sjögren's syndrome is rare. Here we also discuss the treatment of thymoma and the combination of these two diseases.

摘要

一名43岁患有干燥综合征的女性因贫血导致呼吸困难入住我院。入院时她的胸部X光片显示前纵隔肿瘤。基于胸部CT扫描和磁共振成像,我们将此肿瘤诊断为胸腺瘤。因为后者显示胸腺瘤可能已累及纵隔大血管,所以术前使用顺铂、盐酸阿霉素、硫酸长春新碱和环磷酰胺进行化疗。此后,肿瘤连同部分右胸膜被成功切除。胸腺瘤作为干燥综合征的并发症很罕见。在此我们还讨论了胸腺瘤的治疗以及这两种疾病的合并情况。

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