人类滥用的103种药物的习惯性、中毒性和致死性浓度。
Habitual, toxic, and lethal concentrations of 103 drugs of abuse in humans.
作者信息
Repetto M R, Repetto M
机构信息
National Institute of Toxicology, Seville, Spain.
出版信息
J Toxicol Clin Toxicol. 1997;35(1):1-9. doi: 10.3109/15563659709001158.
BACKGROUND
Poisoning caused by drugs of abuse or commonly used addictive medicines occurs with relative frequency and often leads, either directly or indirectly, to death. The interpretation of the blood and urine concentrations is, however, a complex and difficult problem.
METHODS
We have reviewed the published data and subjected them to selection and unification on the basis of conservative criteria and our own experience.
RESULTS
A compilation of the concentrations of 103 drugs of abuse in whole blood, serum/plasma, and urine, during habitual or therapeutic use and as found in toxic or lethal poisoning is given.
CONCLUSIONS
The table presented can be helpful in interpretation of the drug concentrations encountered in clinical, toxicological, and forensic cases.
背景
滥用药物或常用成瘾性药物引起的中毒相对常见，且常常直接或间接导致死亡。然而，血液和尿液浓度的解读是一个复杂且困难的问题。
方法
我们回顾了已发表的数据，并根据保守标准和我们自己的经验对其进行筛选和统一。
结果
给出了103种滥用药物在全血、血清/血浆和尿液中习惯性或治疗性使用时以及在中毒或致死性中毒中所发现的浓度汇编。
结论
所呈现的表格有助于解读临床、毒理学和法医案例中遇到的药物浓度。
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