Eyeson-Annan M, Peterken C, Brown B, Atchison D
Centre for Eye Research, School of Optometry, Queensland University of Technology, Brisbane, Queensland, Australia.
Aviat Space Environ Med. 1996 Oct;67(10):955-62.
The relative importance of visual and vestibular information in the etiology of motion sickness (MS) is not well understood, but these factors can be manipulated by inducing Coriolis and pseudo-Coriolis effects in experimental subjects.
We hypothesized that visual and vestibular information are equivalent in producing MS. The experiments reported here aim, in part, to examine the relative influence of Coriolis and pseudo-Coriolis effects in inducing MS.
We induced MS symptoms by combinations of whole body rotation and tilt, and environment rotation and tilt, in 22 volunteer subjects. Subjects participated in all of the experiments with at least 2 d between each experiment to dissipate after-effects. We recorded MS signs and symptoms when only visual stimulation was applied, when only vestibular stimulation was applied, and when both visual and vestibular stimulation were applied under specific conditions of whole body and environmental tilt.
Visual stimuli produced more symptoms of MS than vestibular stimuli when only visual or vestibular stimuli were used (ANOVA F = 7.94, df = 1, 21 p = 0.01), but there was no significant difference in MS production when combined visual and vestibular stimulation were used to produce the Coriolis effect or pseudo-Coriolis effect (ANOVA: F = 0.40, df = 1, 21 p = 0.53). This was further confirmed by examination of the order in which the symptoms occurred and the lack of a correlation between previous experience and visually induced MS.
Visual information is more important than vestibular input in causing MS when these stimuli are presented in isolation. In conditions where both visual and vestibular information are present, cross-coupling appears to occur between the pseudo-Coriolis effect and the Coriolis effect, as these two conditions are not significantly different in producing MS symptoms.
视觉和前庭信息在晕动病（MS）病因中的相对重要性尚未完全明确，但在实验对象中可通过诱导科里奥利效应和伪科里奥利效应来操控这些因素。
我们假设视觉和前庭信息在引发MS方面作用相当。本文所报告的实验部分旨在研究科里奥利效应和伪科里奥利效应在诱发MS中的相对影响。
我们通过全身旋转与倾斜以及环境旋转与倾斜的组合，在22名志愿者身上诱发MS症状。受试者参与所有实验，每次实验间隔至少2天以消除后效应。我们记录了在仅施加视觉刺激、仅施加前庭刺激以及在全身和环境倾斜的特定条件下同时施加视觉和前庭刺激时的MS体征和症状。
当仅使用视觉或前庭刺激时，视觉刺激比前庭刺激产生更多的MS症状（方差分析F = 7.94，自由度df = 1, 21，p = 0.01），但在使用联合视觉和前庭刺激产生科里奥利效应或伪科里奥利效应时，诱发MS方面无显著差异（方差分析：F = 0.40，自由度df = 1, 21，p = 0.53）。通过检查症状出现的顺序以及既往经验与视觉诱发MS之间缺乏相关性，进一步证实了这一点。
当这些刺激单独呈现时，视觉信息在引发MS方面比前庭输入更重要。在视觉和前庭信息均存在的情况下，伪科里奥利效应和科里奥利效应之间似乎发生了交叉耦合，因为这两种情况在产生MS症状方面无显著差异。
