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[肝脾超声检查在曼氏血吸虫病流行区监测中的价值(塞内加尔理查德托尔地区的一项研究)]

[Value of hepatosplenic ultrasonography in the surveillance of Schistosoma mansoni endemics (a study conducted in the Richard Toll region of Senegal)].

作者信息

Lanuit R, Klotz F, Delegue P, Ribeau G, Capron A

机构信息

Service de Radiologie, Hôpital de Saint Louis, Dakar, Sénégal.

出版信息

Med Trop (Mars). 1996;56(3):271-4.

PMID:9026595
Abstract

Abdominal ultrasound is a reliable and reproducible technique for monitoring the progression of hepatosplenic schistomiasis. It was used in the framework of the @Hope" program against endemic Schistosoma mansoni in the Senegal River region. A total of 166 patients presenting Schistosoma mansoni eggs in stools were divided into age groups with a sex ratio of 1. All patients underwent the same ultrasound examination including measurement of the liver and assessment of the branches of the portal vein system. Our findings indicated that highly sensitive hypertrophy of the left lobe of the liver occurs early since this feature was observed in all patients over the age of 15 years. Alterations of the portal system were observed in 73% of patients but were moderate, stage 1, in the zone where incidence of positive stools is over 90%. Grade III lesions were only found in patients over 23 years of age. Although these lesions accounted for 4% of the cases, this finding underscores the need for surveillance in a region where infestation became endemic less then ten years ago raising fears that severe schistosomal portal hypertension would become widespread. A mobile ultrasonographic surveillance unit would be useful in the region.

摘要

腹部超声是监测肝脾血吸虫病进展的一种可靠且可重复的技术。它被用于塞内加尔河地区针对曼氏血吸虫病流行的“希望”项目框架内。共有166例粪便中检出曼氏血吸虫卵的患者按年龄分组,男女比例为1。所有患者均接受相同的超声检查,包括肝脏测量和门静脉系统分支评估。我们的研究结果表明,肝左叶高度敏感的肥大出现得较早,因为在所有15岁以上的患者中均观察到这一特征。73%的患者观察到门静脉系统改变,但在粪便阳性率超过90%的区域为中度,即1期。III级病变仅在23岁以上的患者中发现。尽管这些病变占病例的4%,但这一发现凸显了在一个不到十年前感染成为地方病的地区进行监测的必要性,这引发了人们对严重血吸虫性门静脉高压症将广泛传播的担忧。一个移动超声监测单位在该地区将很有用。

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