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[血液肿瘤诊所进行骨髓和外周血干细胞移植期间出血性膀胱炎的预防]

[The prevention of hemorrhagic cystitis during the performance of bone marrow and peripheral blood stem cell transplantation in the hematologic cancer clinic].

作者信息

Uss A L, Milanovich N F, Snegir' V M, Zmachinskiĭ V A, Skriagin A E

出版信息

Ter Arkh. 1996;68(10):49-52.

PMID:9026944
Abstract

Investigators from Belarus Center for bone marrow transplantation examined the efficacy of preventing hemorrhagic cystitis induced by high-dose cyclophosphamide in preparation for hemopoiesis precursor transplantation in 22 patients with hematological diseases. The proposed preventive method implied administration of mesna (2-merkaptoetan-sulphonate) and alkaline forced diuresis. Its effectiveness was found high.

摘要

白俄罗斯骨髓移植中心的研究人员对22例血液病患者在造血前体细胞移植准备过程中,预防大剂量环磷酰胺所致出血性膀胱炎的疗效进行了研究。所提出的预防方法包括给予美司钠(2-巯基乙烷磺酸盐)和碱性强制利尿。结果发现其有效性很高。

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