Demina A A, Martynov Iu V
Zh Mikrobiol Epidemiol Immunobiol. 1996 Jul-Aug(4):57-61.
In this work the specific features of the epidemiological rise of morbidity in meningococcal infection in Russia for the period of 25 years are analyzed. Some factors influencing the intensity of the disease, such as etiology, specific features arising from the age of patients, social and territorial factors, are analyzed. Two waves of epidemic have been established in a single epidemic cycle. The first wave of epidemic was caused by meningococci of group A and characterized by the prevalence of city-dwellers among the patients; the second wave was caused by meningococci of groups A and B with the prevalence of the latter, especially during the period of the slump of the wave. The "Asiatic" and "European" types of morbidity were distinguished (in Moscow and St. Petersburg). The analysis of the epidemic cycle of meningococcal infection indicates the expediency of the development of new specific wide-profile preparation for prophylaxis.
本研究分析了俄罗斯25年间脑膜炎球菌感染发病率在流行病学上上升的具体特征。分析了一些影响疾病强度的因素,如病因、患者年龄所产生的特定特征、社会和地域因素。在一个单一的流行周期内确定了两波疫情。第一波疫情由A群脑膜炎球菌引起,其特征是患者中城市居民占多数;第二波疫情由A群和B群脑膜炎球菌引起,其中B群脑膜炎球菌占优势,特别是在疫情低谷期。区分了(莫斯科和圣彼得堡的)“亚洲型”和“欧洲型”发病率。对脑膜炎球菌感染流行周期的分析表明,研发新型广谱特异性预防制剂是适宜的。