Pavlova L I, Gaevyĭ M D
Farmakol Toksikol. 1977 Jul-Aug;40(4):412-4.
The investigation was carried out on anesthetized cats under controlled respiration. The tonicity of cranial vessels was judged about by the perfusion pressure figures in the system of intra- and extra-cranial vessels. With its intravenous and intracarotid administration diaethiphenum lowered the one of intra- and extra-cranial vessels. An intravenous introduction of its high doses was followed also by a fall of the total arterial pressure. An effect on the brain vasculature similar to that of diaethiphenum is also produced by diethylstibestrol.
该研究在呼吸受控的麻醉猫身上进行。通过颅内和颅外血管系统中的灌注压数值来判断颅血管的张力。通过静脉内和颈内给药，双乙苯胺降低了颅内和颅外血管的张力。静脉注射高剂量的双乙苯胺后，总动脉压也会下降。己烯雌酚对脑血管系统也产生了与双乙苯胺类似的作用。
