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[二乙苯丙胺对脑血管张力和全身动脉血压的影响]

[Effect of diethyphen on cerebral vessel tonus and on general arterial pressure].

作者信息

Pavlova L I, Gaevyĭ M D

出版信息

Farmakol Toksikol. 1977 Jul-Aug;40(4):412-4.

PMID:902739
Abstract

The investigation was carried out on anesthetized cats under controlled respiration. The tonicity of cranial vessels was judged about by the perfusion pressure figures in the system of intra- and extra-cranial vessels. With its intravenous and intracarotid administration diaethiphenum lowered the one of intra- and extra-cranial vessels. An intravenous introduction of its high doses was followed also by a fall of the total arterial pressure. An effect on the brain vasculature similar to that of diaethiphenum is also produced by diethylstibestrol.

摘要

该研究在呼吸受控的麻醉猫身上进行。通过颅内和颅外血管系统中的灌注压数值来判断颅血管的张力。通过静脉内和颈内给药,双乙苯胺降低了颅内和颅外血管的张力。静脉注射高剂量的双乙苯胺后,总动脉压也会下降。己烯雌酚对脑血管系统也产生了与双乙苯胺类似的作用。

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