Nakano E, Iwasaki T, Osanai T, Yamamoto K, Miyauchi M
Department of Ophthalmology, Tokyo Medical College, Japan.
Nippon Ganka Gakkai Zasshi. 1997 Jan;101(1):64-8.
We examined the frequency and types of ocular complications that developed in 560 eyes of 280 patients with atopic dermatitis at the Department of Dermatology, Tokyo Medical College Hospital. Mild ocular involvement included blepharitis in 294 eyes (52.5%), conjunctivitis in 221 eyes (39.5%), and superficial punctate keratopathy in 65 eyes (11.6%). More serious ocular complications leading to decreased visual function occurred in 133 eyes (23.8%) that developed lens opacities, and 34 eyes (6.0%) that developed retinal break or retinal detachment. Because of the presence of abnormalities in the peripheral retina, we believe that a pathogenic factor may have been present in the vitreous of these atopic dermatitis patients. Many of our patients with atopic dermatitis had serious ocular complications in the absence of ocular symptoms. Thus it is important to conduct a thorough ophthalmological examination in the early period of disease in atopic dermatitis patients, both for the management of early but serious ocular complications, as well as for the preservation of visual function.
我们对东京医科大学医院皮肤科280例特应性皮炎患者的560只眼睛所出现的眼部并发症的频率和类型进行了检查。轻度眼部受累包括睑缘炎294只眼（52.5%）、结膜炎221只眼（39.5%）、浅层点状角膜炎65只眼（11.6%）。导致视功能下降的更严重眼部并发症发生在133只眼（23.8%），这些眼睛出现了晶状体混浊，以及34只眼（6.0%），这些眼睛出现了视网膜裂孔或视网膜脱离。由于周边视网膜存在异常，我们认为这些特应性皮炎患者的玻璃体中可能存在致病因素。我们的许多特应性皮炎患者在没有眼部症状的情况下出现了严重的眼部并发症。因此，对于特应性皮炎患者，在疾病早期进行全面的眼科检查非常重要，这既有助于早期严重眼部并发症的管理，也有助于视功能的保存。
