Carmi Esther, Defossez-Tribout Caroline, Ganry Olivier, Cene Sylvain, Tramier Blaise, Milazzo Solange, Lok Catherine
Department of Dermatology, Hôpital Sud, Amiens, France.
Acta Derm Venereol. 2006;86(6):515-7. doi: 10.2340/00015555-0163.
Ocular complications of atopic dermatitis in adults are blepharitis, keratoconjunctivitis, keratoconus, uveitis, subcapsular cataract and retinal detachment. Their frequency varies from 25% to 50%. The aim of this study was to assess the frequency and type of ophthalmological complications in children with atopic dermatitis. The secondary objectives of the study were to determine whether there is a correlation between severity of atopic dermatitis, face involvement, external ocular signs and the presence of ocular complications, and to identify risk factors for ophthalmological complications. Thirty-seven boys and 22 girls, mean age 36.2 months, with atopic dermatitis were examined. Atopic dermatitis severity was mild according to the SCORAD index (31.6 +/- 17.0). Fifteen (25.4%) children had external ocular signs, one had a nuclear cataract, 11 had benign papillofollicular conjunctivitis, one had purulent bacterial conjunctivitis, one had chronic atopic blepharitis and one had amblyopia. Severity of atopic dermatitis, face involvement, and external ocular signs did not seem to influence the incidence of ocular involvement. This study suggests that severe ocular complications are rare in young children with mild atopic dermatitis.
成人特应性皮炎的眼部并发症包括睑缘炎、角结膜炎、圆锥角膜、葡萄膜炎、囊下白内障和视网膜脱离。其发生率在25%至50%之间。本研究的目的是评估特应性皮炎患儿眼部并发症的发生率和类型。该研究的次要目标是确定特应性皮炎的严重程度、面部受累情况、眼部外部体征与眼部并发症的存在之间是否存在相关性,并确定眼部并发症的危险因素。对37名男孩和22名女孩(平均年龄36.2个月)进行了特应性皮炎检查。根据SCORAD指数,特应性皮炎严重程度为轻度(31.6 +/- 17.0)。15名(25.4%)儿童有眼部外部体征,1名有核性白内障,11名有良性乳头滤泡性结膜炎,1名有脓性细菌性结膜炎,1名有慢性特应性睑缘炎,1名有弱视。特应性皮炎的严重程度、面部受累情况和眼部外部体征似乎并未影响眼部受累的发生率。本研究表明,轻度特应性皮炎幼儿中严重眼部并发症罕见。