蕈样肉芽肿患者 HLA 抗原的分布

Distribution of HLA antigens in patients with mycosis fungoides.

作者信息

Dick H M, Mackie R

出版信息

Dermatologica. 1977;155(5):275-82. doi: 10.1159/000250978.

Abstract

19 patients with plaque-style mycosis fungoides have undergone determination of HLA antigen distribution. Deviations from the expected distribution frequency occurred with the antigens of the W19 group comprising A29, W30, W31 and W32 and of B8 and A1. The W19 group deviation was statistically significant (chi2 = 9.7 p value less than 0.005). The significance of this observation in relation to reported immunological abnormalities in mycosis fungoides is discussed.

摘要

19例斑块型蕈样肉芽肿患者接受了HLA抗原分布测定。在包括A29、W30、W31和W32的W19组抗原以及B8和A1抗原方面出现了与预期分布频率的偏差。W19组的偏差具有统计学意义（卡方=9.7，p值小于0.005）。讨论了这一观察结果与报道的蕈样肉芽肿免疫异常的关系。