de Deyne C, Vandekerckhove T, Decruyenaere J, Colardyn F
Department of Intensive Care, University Hospital UZG, Gent, Belgium.
Acta Neurochir (Wien). 1996;138(12):1409-15. doi: 10.1007/BF01411119.
Jugular bulb oximetry provides the first bedside, continuously available information on cerebral perfusion adequacy. An extensive analysis was made of all jugular bulb oxygen saturation (SjO2) data obtained in 50 patients suffering from severe head injury. A total of 176 periods (more than 30 minutes) with reliable, abnormal SjO2-values was observed, with 62 desaturation periods (SjO2 < 55%) and 114 high SjO2-periods (SjO2 > 80%). Jugular desaturation periods were predominantly observed in the first 2 days of monitoring and seemed the most closely correlated to lowered cerebral perfusion pressure and lowered arterial carbon dioxide tension. The high SjO2-values were more equally distributed over the first 5 days of monitoring and seemed mostly correlated to increased arterial carbon dioxide tension. Highlights of the general management of severely head injured patients is discussed, focussing attention on the importance of cerebral perfusion pressure and normoventilation.
颈静脉球血氧饱和度测定可在床边首次持续提供有关脑灌注充足性的信息。对50例重型颅脑损伤患者获得的所有颈静脉球血氧饱和度（SjO2）数据进行了广泛分析。共观察到176个时间段（超过30分钟）的可靠异常SjO2值，其中62个为血氧饱和度降低期（SjO2<55%），114个为高SjO2期（SjO2>80%）。颈静脉血氧饱和度降低期主要出现在监测的头2天，似乎与脑灌注压降低和动脉二氧化碳分压降低关系最为密切。高SjO2值在监测的前5天分布更为均匀，似乎主要与动脉二氧化碳分压升高有关。讨论了重型颅脑损伤患者综合管理的要点，重点关注脑灌注压和正常通气的重要性。
