Ing T S, Patel B P, Patel J A, Patel N K, Yu A W, Osman A, Zhou F Q
Department of Medicine, Loyola University Chicago, Stritch School of Medicine, Maywood, USA.
Int J Artif Organs. 1996 Dec;19(12):700-3.
Neutrophil superoxide formation was similar when cells were incubated in self-made, non-autoclaved pH 7.4, lactate-based peritoneal dialysis solutions or in their self-made, non-autoclaved, pH 7.4, bicarbonate-based counterparts. On the other hand, commercially available, autoclaved, pH 7.4, lactate-based peritoneal dialysis solutions resulted in inhibition of superoxide production when compared to their self-made, non-autoclaved, pH 7.4, lactate-based or bicarbonate-based counterparts. The cause for this inhibition of superoxide generation is at present unknown.
当细胞在自制的、未高压灭菌的pH 7.4乳酸盐基腹膜透析液或其自制的、未高压灭菌的pH 7.4碳酸氢盐基对应溶液中孵育时，中性粒细胞超氧化物的形成相似。另一方面，与自制的、未高压灭菌的pH 7.4乳酸盐基或碳酸氢盐基腹膜透析液相比，市售的、高压灭菌的pH 7.4乳酸盐基腹膜透析液会导致超氧化物产生受到抑制。目前尚不清楚这种超氧化物生成抑制的原因。
