Ing T S, Yu A W, Podila P V, Zhou F Q, Kun E W, Strippoli P, Nawab Z M
Department of Medicine, Veterans Affairs Hospital, Hines, Illinois.
Int J Artif Organs. 1994 Apr;17(4):191-4.
Exposure of human neutrophils to conventional, acidic, lactate-based peritoneal dialysis solutions for 5 minutes results in a depression of superoxide generation. In spite of restoration of extracellular pH to 7.4, these stunned cells failed to recover their ability to generate the anion after a period of an hour.
将人类中性粒细胞暴露于传统的、酸性的、基于乳酸盐的腹膜透析液中5分钟会导致超氧化物生成减少。尽管细胞外pH恢复到了7.4,但这些“休克”细胞在一小时后仍未能恢复其生成该阴离子的能力。