Nuechterlein K H, Subotnik K L
Department of Psychiatry and Biobehavioral Sciences, UCLA 90024-6968, USA.
Psychiatry. 1996 Winter;59(4):389-92. doi: 10.1080/00332747.1996.11024778.
The presentation of Ms. E. by Hawkins and Cooper provides an excellent discussion of the diverse ways in which clinicians and clinical researchers are currently conceptualizing neurocognitive deficits within severe psychiatric disorders. The thorough neuropsychological evaluation of this patient provided a wealth of information that was completely missed by the Mini-Mental State Exam (MMSE; Folstein et al. 1975). As Hawkins and Cooper point out, the tendency of some clinicians to discount the role of neuropsychological deficiency in the face of adequate MMSE scores and evident psychiatric symptoms is not justified by the relevant clinical research literature. Furthermore, recent developments in scientific conceptions of the role of neurocognitive deficits in the more severe psychiatric disorders, such as schizophrenia, schizoaffective disorder, and bipolar mood disorder, deserve more attention in clinical practice.
霍金斯和库珀对E女士的介绍,出色地探讨了临床医生和临床研究人员目前在严重精神疾病中对神经认知缺陷进行概念化的多种方式。对该患者进行的全面神经心理学评估提供了大量信息,而简易精神状态检查表(MMSE;福尔斯坦等人,1975年)却完全遗漏了这些信息。正如霍金斯和库珀所指出的,面对MMSE分数正常且存在明显精神症状时,一些临床医生忽视神经心理学缺陷作用的倾向,在相关临床研究文献中并无依据。此外,神经认知缺陷在诸如精神分裂症、分裂情感性障碍和双相情感障碍等更严重精神疾病中作用的科学概念的最新进展,在临床实践中应得到更多关注。