Boudewyns A, De Cock W, Willemen M, Wagemans M, De Backer W, Van de Heyning P H
Dept of Otorhinolaryngology, Antwerp University, UIA, Belgium.
Eur Respir J. 1997 Jan;10(1):129-32. doi: 10.1183/09031936.97.10010129.
Arousals are more numerous in heavy snorers than in nonsnorers and might be a cause of excessive daytime sleepiness (EDS) in these patients. The present study investigated whether treatment of snoring by uvulopalatopharyngoplasty (UPPP) had an influence on sleep microstructure in nonapnoeic snorers. The polysomnographic records of 10 nonapnoeic snorers were reviewed retrospectively and arousals scored according to the American Sleep Disorders Association (ASDA) 3 s definition. Scores for snoring, EDS and polysomnographic data were compared before and after UPPP (mean (+/-SD) time interval 249 +/- 183 days). UPPP resulted in a subjective improvement of snoring and a significant decrease in the arousal index (mean 14.6, 95% confidence interval (95% CI) 8.5-20.8 vs mean 9.1, 95% CI 6.6-11.5) (p = 0.01). EDS and the amount of slow-wave sleep remained unchanged. Uvulopalatopharyngoplasty resulted in an improvement of subjective snoring and a significant decrease of arousals in nonapnoeic snorers. Although these data do not provide any insight into whether the improvement observed can be maintained on a long-term basis, uvulopalatopharyngoplasty can be considered as a useful treatment modality to reduce sleep fragmentation and snoring in nonapnoeic snorers.
重度打鼾者的觉醒次数比不打鼾者更多,这可能是这些患者日间过度嗜睡(EDS)的一个原因。本研究调查了悬雍垂腭咽成形术(UPPP)治疗打鼾对非呼吸暂停性打鼾者睡眠微结构的影响。回顾性分析了10例非呼吸暂停性打鼾者的多导睡眠图记录,并根据美国睡眠障碍协会(ASDA)的3秒定义对觉醒进行评分。比较了UPPP前后的打鼾评分、EDS评分和多导睡眠图数据(平均(±标准差)时间间隔为249±183天)。UPPP使打鼾主观症状得到改善,觉醒指数显著降低(平均值分别为14.6,95%置信区间(95%CI)8.5 - 20.8和平均值9.1,95%CI 6.6 - 11.5)(p = 0.01)。EDS和慢波睡眠量保持不变。悬雍垂腭咽成形术可改善非呼吸暂停性打鼾者的主观打鼾症状,并显著减少觉醒次数。尽管这些数据并未提供关于所观察到的改善能否长期维持的任何见解,但悬雍垂腭咽成形术可被视为一种有用的治疗方式,用于减少非呼吸暂停性打鼾者的睡眠片段化和打鼾症状。