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[烧伤病房的医院感染。一项为期一年的前瞻性研究结果]

[Nosocomial infections in a burns unit. Results of a prospective study over a year].

作者信息

Cremer R, Ainaud P, Le Bever H, Fabre M, Carsin H

机构信息

Centre de traitement des brûlés, hôpital d'instruction des Armées Percy, Clamart, France.

出版信息

Ann Fr Anesth Reanim. 1996;15(5):599-607. doi: 10.1016/0750-7658(96)82125-3.

Abstract

OBJECTIVES

To assess nosocomial infections in a burn care centre, to identify patients' infection risk factors at the time of admission and factors of monthly variations of infection incidence.

STUDY DESIGN

Prospective survey, from October 1992 to September 1993.

PATIENTS AND METHOD

The study included 140 patients staying for more than two days in a 22-bed burn unit. Nosocomial infection criteria were derived from the 1988 CDC criteria. Incidence rates of infection were calculated. Infected and noninfected patients were compared. Each monthly infection incidence was compared with six unit activity indicators.

RESULTS

Fifty-six patients developed 132 infections. The overall incidence was 94%. Incidence density was 25 infections per 1,000 days of care. The distribution of infected sites was: skin (30%), intravascular catheters (25%), blood (22%), urinary tract (18%), respiratory tract (5%). The most frequent pathogens were Pseudomonas sp (49%), Staphylococcus sp (18%), Escherichia coli (18%), and Streptococcus faecalis (10%). They were characterized by a good antibiotic sensitivity. Each common burn severity index was predictive of nosocomial infections. Facial, perineal and respiratory lesions were also linked to infection. There was a positive correlation between the peak of nosocomial infections in the unit during a month and the peak of activity during the foregoing one.

CONCLUSION

Incidence rates of infection were high, as 40% of the population was concerned. Choosing reliable infection criteria was the most difficult problem to solve.

摘要

目的

评估一家烧伤护理中心的医院感染情况,确定患者入院时的感染风险因素以及感染发生率的月度变化因素。

研究设计

1992年10月至1993年9月的前瞻性调查。

患者与方法

该研究纳入了140名在拥有22张床位的烧伤病房住院超过两天的患者。医院感染标准源自1988年美国疾病控制与预防中心(CDC)的标准。计算感染发生率。对感染患者和未感染患者进行比较。将每月的感染发生率与六个病房活动指标进行比较。

结果

56名患者发生了132次感染。总体发生率为94%。感染密度为每1000个护理日25次感染。感染部位分布为:皮肤(30%)、血管内导管(25%)、血液(22%)、尿路(18%)、呼吸道(5%)。最常见的病原体是假单胞菌属(49%)、葡萄球菌属(18%)、大肠杆菌(18%)和粪肠球菌(10%)。它们对抗生素具有良好的敏感性。每个常见的烧伤严重程度指数都可预测医院感染。面部、会阴部和呼吸道损伤也与感染有关。一个月内病房医院感染高峰与前一个月的活动高峰之间存在正相关。

结论

感染发生率很高,涉及40%的人群。选择可靠的感染标准是最难解决的问题。

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