Taytard A, Cousson F
Service de Maladies Respiratoires, Hôpital du Haut-Lévêque, Centre Hospitalo-Universitaire de Bordeaux.
Rev Pneumol Clin. 1996;52(6):379-85.
Improvement in the bronchial obstruction is the aim of treatment for patients with chronic bronchitis. In this work, we attempted to identify subjective psychosocial and neurophysiological factors which are essential for understanding the quality of life in these patients. The study included 77 male patients under 80 years of age who were diagnosed as having chronic bronchitis by their family physician. In all cases, the disease state was stable without any other complication or co-morbidity. Each patient responded to a questionnaire and underwent volume-flow tests. The population was divided into 2 groups by VEMS: VEMS > or = 50% (n = 48) and VEMS < 50 (n = 19). Main component analysis followed by varimax rotation was used to analyse data. A Cronbach coefficient was calculated to measure data skewness. The Pearson correlations were calculated for the different factors. Mean intergroup means were compared with the unpaired t test. Data analysis demonstrated two physical factors: dyspnea and bronchial obstruction; 4 psychological factors: anxiety, impotency/hopeless feeling, depression, fatigue: and one psychological trait. Key symptoms of chronic bronchitis developed in patients with affective states contributing to the patient's subjective description of his disease and influencing therapeutic management. A better understanding of these patients is needed to improve treatment of chronic bronchitis.
改善支气管阻塞是慢性支气管炎患者的治疗目标。在这项研究中，我们试图确定主观心理社会因素和神经生理因素，这些因素对于理解这些患者的生活质量至关重要。该研究纳入了77名80岁以下被家庭医生诊断为慢性支气管炎的男性患者。在所有病例中，疾病状态稳定，无任何其他并发症或合并症。每位患者都回答了一份问卷并接受了容积-流量测试。根据最大呼气中期流速（VEMS）将研究对象分为两组：VEMS≥50%（n = 48）和VEMS＜50（n = 19）。采用主成分分析并经方差最大旋转法对数据进行分析。计算克朗巴哈系数以测量数据偏度。计算不同因素间的皮尔逊相关性。采用非配对t检验比较组间均值。数据分析显示有两个身体因素：呼吸困难和支气管阻塞；4个心理因素：焦虑、性无能/绝望感、抑郁、疲劳；以及一个心理特质。慢性支气管炎的关键症状出现在情感状态影响患者对自身疾病主观描述并影响治疗管理的患者中。为了改善慢性支气管炎的治疗，需要更好地了解这些患者。
