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乙状结肠系膜血管外皮细胞瘤:一例免疫组化结果报告。

Hemangiopericytoma of the sigmoid mesentery: report of a case with immunohistochemical findings.

作者信息

Nakagawa T, Shinoda Y, Masuko Y, Ohshima T, Shirota K, Yoshida Y, Ogawa K, Uchino J

机构信息

Department of Surgery, Furano Kyokai Hospital, Japan.

出版信息

Surg Today. 1997;27(1):64-7. doi: 10.1007/BF01366942.

Abstract

Hemangiopericytoma has been described in various sites in the body but only rarely in the mesocolon. This report describes the clinical course of an 83-year-old man whose mesosigmoidal tumor (hemangiopericytoma) was resected on 11 November 1994. Immunostaining was done with the following primary antibodies: alpha-actin, vimentin, factor VIII-related antigen, chromogranin, and S-100. Staining for factor VIII-related antigen was strongly positive in the endothelial cells of the capillaries, but negative in the tumor cells. The tumor cells contained immunoreactive vimentin, but demonstrated no alpha-actin, chromogranin, or S-100. Since the operation, the patient has been disease-free for 11 months.

摘要

血管外皮细胞瘤可见于身体的各个部位,但在结肠系膜中极为罕见。本报告描述了一名83岁男性的临床病程,其乙状结肠系膜肿瘤(血管外皮细胞瘤)于1994年11月11日切除。使用以下一抗进行免疫染色:α-肌动蛋白、波形蛋白、因子VIII相关抗原、嗜铬粒蛋白和S-100。因子VIII相关抗原染色在毛细血管内皮细胞中呈强阳性,但在肿瘤细胞中呈阴性。肿瘤细胞含有免疫反应性波形蛋白,但未显示α-肌动蛋白、嗜铬粒蛋白或S-100。自手术以来,患者已无病生存11个月。

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