Fleischmajer R, Perlish J S
J Invest Dermatol. 1977 Oct;69(4):379-82. doi: 10.1111/1523-1747.ep12510308.
The purpose of this study was to estimate [3H] thymidine labeling of endothelial cells of skin capillaries in localized scleroderma (LS) and systemic scleroderma (SS). Skin specimens from 14 patients with SS, 5 with LS, and 9 matched controls were studied by in vitro autoradiography. Capillaries from patients with SS showed a statistically significant increase in endothelial cell labeling when compared to vessels from controls (p less than 0.0005).
本研究的目的是评估局限性硬皮病（LS）和系统性硬皮病（SS）中皮肤毛细血管内皮细胞的[3H]胸苷标记情况。通过体外放射自显影术对14例SS患者、5例LS患者以及9例匹配的对照者的皮肤标本进行了研究。与对照组的血管相比，SS患者的毛细血管内皮细胞标记显示出具有统计学意义的增加（p<0.0005）。
