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使用神经网络预测创伤死亡率。

Prediction of trauma mortality using a neural network.

作者信息

Izenberg S D, Williams M D, Luterman A

机构信息

Department of Surgery, University of South Alabama Medical Center, Mobile, USA.

出版信息

Am Surg. 1997 Mar;63(3):275-81.

PMID:9036899
Abstract

A neural network is a computerized construct consisting of input neurons (which process input data) connected to hidden neurons (to mathematically manipulate values they receive from all the input neurons) connected to output neurons (to output a prediction). Neural networks are created and trained via multiple iterations over data with known results. In 1993, 897 trauma patients were either declared dead in the emergency room (ER; 76 cases), admitted to the intensive care unit (427 cases, 36 deaths), or taken directly to the operating room (394 cases, 29 deaths). Using only data available from the ER, a neural network was created, and 628 cases were randomly selected for training. After 268 iterations, the network was trained to correctly predict death or survival in all 628 cases. This trained network was then tested on the other 269 cases without our providing the death or survival result. Its overall accuracy was 91 per cent (244 of 269 cases). It was able to predict correctly 60 per cent (12 of 20 cases) of the postoperative or post-intensive care unit admission deaths and 90 per cent (26 of 29 cases) of the deaths in the ER. Computerized neural networks can accurately predict a trauma patient's fate based on inital ER presentation. The theory and use of neural networks in predicting clinical outcome will be presented.

摘要

神经网络是一种计算机化结构,由输入神经元(处理输入数据)、连接到隐藏神经元(对从所有输入神经元接收的值进行数学运算)、再连接到输出神经元(输出预测结果)组成。神经网络通过对具有已知结果的数据进行多次迭代来创建和训练。1993年,897名创伤患者要么在急诊室被宣布死亡(76例),要么被送入重症监护病房(427例,36例死亡),要么直接被送往手术室(394例,29例死亡)。仅使用急诊室可得的数据创建了一个神经网络,并随机选择628例进行训练。经过268次迭代后,该网络被训练为能正确预测所有628例患者的死亡或存活情况。然后,在不提供死亡或存活结果的情况下,用这个经过训练的网络对另外269例患者进行测试。其总体准确率为91%(269例中的244例)。它能够正确预测60%(20例中的12例)的术后或重症监护病房入院后的死亡情况,以及90%(29例中的26例)的急诊室死亡情况。计算机化神经网络能够根据急诊室的初始表现准确预测创伤患者的命运。本文将介绍神经网络在预测临床结果中的理论和应用。

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