Yahata T, Kodama S, Kase H, Sekizuka N, Kurabayashi T, Aoki Y, Tanaka K
Department of Obstetrics and Gynecology, Niigata University School of Medicine, Japan.
Gynecol Oncol. 1997 Feb;64(2):274-8. doi: 10.1006/gyno.1996.4541.
Primary choriocarcinoma of the uterine cervix was diagnosed in a 38-year-old Japanese woman 4 months after a normal vaginal, term delivery. The patient had experienced irregular genital bleeding for several weeks. A cervical polypoid tumor was detected by visual inspection 4 months after delivery. Magnetic resonance imaging (MRI) and color Doppler ultrasonography revealed a hypervascular tumor (6 cm) in the uterine cervix. The patient's urinary level of human chorionic gonadotropin (hCG) was 128,000 IU/L. Histological examination of a biopsy of the cervical tumor showed choriocarcinoma. After completion of 2 courses of chemotherapy, the patient underwent a total abdominal hysterectomy. Histological examination of uterus showed no evidence of choriocarcinoma. At present, the patient is free of disease. MRI and color Doppler ultrasonography were useful for diagnosis by detecting the abundant blood flow and central necrosis of the cervical tumor.
一名38岁的日本女性在正常阴道足月分娩4个月后被诊断为原发性子宫颈绒毛膜癌。患者数周来一直有不规则生殖器出血。产后4个月通过视诊发现宫颈有息肉样肿瘤。磁共振成像（MRI）和彩色多普勒超声检查显示子宫颈有一个高血管性肿瘤（6厘米）。患者尿中人绒毛膜促性腺激素（hCG）水平为128,000 IU/L。宫颈肿瘤活检的组织学检查显示为绒毛膜癌。完成2个疗程的化疗后，患者接受了全腹子宫切除术。子宫的组织学检查未发现绒毛膜癌迹象。目前，患者无疾病。MRI和彩色多普勒超声检查通过检测宫颈肿瘤丰富的血流和中央坏死情况，对诊断很有用。
