Kikuchi J, Sasaki T, Ishibashi K, Takaya R, Mori H, Endo H, Shima I, Moritsuka T, Takahashi K
Dept. of Obstetrics and Gynecology, Sendai National Hospital.
Gan To Kagaku Ryoho. 1991 Jun;18(7):1209-12.
A 27-year-old female was admitted to Sendai National Hospital complaining of continuous slight genital bleeding for about one and a half year after incomplete abortion. At first visit, urinary hCG was elevated to 32,000 IU/l and ultrasonography revealed a heterogeneous tumor in the uterus body. After abdominal simple total hysterectomy, the sample was diagnosed pathologically as a uterine choriocarcinoma. The patient was treated with 2 courses of MTX, but this regimen was not so effective. Because of persistent elevation of urinary hCG, 2 courses of etoposide were performed and hCG was rapidly reduced to within LH level. Etoposide (25 mg/day per os) was given to the patient for about three months since hospitalization and now complete remission has been obtained.
