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1
The effect of lung inflation on the control of respiratory frequency in the neonate.肺膨胀对新生儿呼吸频率控制的影响。
J Physiol. 1977 Sep;270(3):653-60. doi: 10.1113/jphysiol.1977.sp011973.
2
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Pediatr Pulmonol. 2006 Aug;41(8):759-64. doi: 10.1002/ppul.20436.
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Electromagnetic inductance plethysmography to measure tidal breathing in preterm and term infants.电磁感应容积描记法测量早产儿和足月儿的潮式呼吸。
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The breathing pattern after breath-holding: the influence of chest position and the drive to breathe.屏气后的呼吸模式：胸部位置及呼吸驱动力的影响。
Q J Exp Physiol Cogn Med Sci. 1978 Oct;63(4):341-52. doi: 10.1113/expphysiol.1978.sp002447.
6
Spontaneously Breathing Preterm Infants Change in Tidal Volume to Improve Lung Aeration Immediately after Birth.出生后即刻改善肺通气，早产儿自主呼吸时潮气量的变化。
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Ventilation and spontaneous breathing at birth of infants with congenital diaphragmatic hernia.先天性膈疝患儿出生时的通气与自主呼吸。
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Evolution of tidal volume requirement during the first 3 weeks of life in infants <800 g ventilated with Volume Guarantee.体重<800g的婴儿使用容量保证通气时，出生后前3周潮气量需求的变化。
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引用本文的文献

1
Transient hypoxia: ventilatory response after vagotomy and during artificial phasic inflation.短暂性缺氧：迷走神经切断术后及人工阶段性充气时的通气反应
Pflugers Arch. 1979 Feb 14;379(1):53-7. doi: 10.1007/BF00622905.

本文引用的文献

1
The response of the new-born baby to inflation of the lungs.新生儿对肺部充气的反应。
J Physiol. 1960 Jun;151(3):551-65. doi: 10.1113/jphysiol.1960.sp006459.
2
[Frequency of breathing as a function of respiratory ventilation during rest].[静息状态下呼吸频率与呼吸通气量的函数关系]
Boll Soc Ital Biol Sper. 1957 Jun;33(6):821-5.
3
Effects of various respiratory stimuli on the depth and frequency of breathing in man.各种呼吸刺激对人体呼吸深度和频率的影响。
Respir Physiol. 1966;1(2):193-205. doi: 10.1016/0034-5687(66)90016-8.
4
On the regulation of depth and rate of breathing.论呼吸深度与频率的调节。
J Physiol. 1972 Apr;222(2):267-95. doi: 10.1113/jphysiol.1972.sp009797.
5
A new nosepiece for measuring ventilation in preterm infants.一种用于测量早产儿通气的新型鼻部件。
J Appl Physiol. 1972 Mar;32(3):423-4. doi: 10.1152/jappl.1972.32.3.423.
6
Influence of lung inflation on respiratory control in neonates.肺膨胀对新生儿呼吸控制的影响。
J Appl Physiol. 1974 Apr;36(4):426-9. doi: 10.1152/jappl.1974.36.4.426.
7
Mean and breath-by-breath pattern of breathing in man during steady-state exercise.人体在稳态运动期间的平均呼吸模式和逐次呼吸模式。
J Physiol. 1975 Oct;251(3):657-69. doi: 10.1113/jphysiol.1975.sp011114.

肺膨胀对新生儿呼吸频率控制的影响。

The effect of lung inflation on the control of respiratory frequency in the neonate.

作者信息

Boychuk R B, Rigatto H, Seshia M M

出版信息

J Physiol. 1977 Sep;270(3):653-60. doi: 10.1113/jphysiol.1977.sp011973.

DOI:10.1113/jphysiol.1977.sp011973
PMID:903908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1353536/
Abstract
  1. We have measured the relationship between tidal volume (V(T)) and the duration of inspiration (T(i)) and expiration (T(e)) for individual breaths (30 in each steady state).2. Ten pre-term and ten term infants were studied during steady state while breathing 21% O(2), then 21% O(2) plus 2 and 4% CO(2).3. In all infants, the average T(i) at the various chemical drives was remarkably constant, and did not decrease as the tidal volume increased. However, at any given level of respiratory drive, there was a slightly positive correlation of V(T) with T(i) and T(e) in 95% of the cases.4. In four pre-term and two term infants, T(e) increased with increasing respiratory drive. In these infants, therefore, instantaneous respiratory frequency (1/(T(i) + T(e))) actually decreased as lung volume increased.5. We suggest that T(i) is independent of V(T) within the range of volumes studied (up to 2 times the resting V(T)) and that changes in instantaneous respiratory frequency (1/(T(i) + T(e))) result from changes in T(e).
摘要

  1. 我们测量了单次呼吸（每个稳定状态下30次）的潮气量（V(T)）与吸气时间（T(i)）和呼气时间（T(e)）之间的关系。

  2. 对10名早产儿和10名足月儿在稳定状态下进行研究，他们先后呼吸21% O₂，然后是21% O₂加2%和4% CO₂。

  3. 在所有婴儿中，在不同化学驱动下的平均T(i)非常恒定，且不会随着潮气量增加而减少。然而，在任何给定的呼吸驱动水平下，95%的情况下V(T)与T(i)和T(e)存在轻微的正相关。

  4. 在4名早产儿和2名足月儿中，T(e)随着呼吸驱动增加而增加。因此，在这些婴儿中，随着肺容量增加，瞬时呼吸频率（1/(T(i) + T(e))）实际上会降低。

  5. 我们认为在所研究的容量范围内（高达静息V(T)的2倍），T(i)与V(T)无关，且瞬时呼吸频率（1/(T(i) + T(e))）的变化是由T(e)的变化引起的。