生长锥信号传导中的Rho家族GTP结合蛋白。
Rho family GTP-binding proteins in growth cone signalling.
作者信息
Luo L, Jan L Y, Jan Y N
机构信息
Howard Hughes Medical Institute, Department of Physiology, University of California at San Francisco, California 94143, USA.
出版信息
Curr Opin Neurobiol. 1997 Feb;7(1):81-6. doi: 10.1016/s0959-4388(97)80124-9.
PMID:9039798
Abstract
Rho family GTP-binding proteins regulate various aspects of the actin cytoskeleton in a wide variety of organisms. Recent evidence suggests that they may also be important components of the signalling pathways that link the reception of extracellular cues to the regulation of the cytoskeleton in neuronal growth cones.
摘要
Rho家族GTP结合蛋白在多种生物体中调节肌动蛋白细胞骨架的各个方面。最近的证据表明，它们也可能是信号通路的重要组成部分，这些信号通路将细胞外信号的接收与神经元生长锥中细胞骨架的调节联系起来。
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