Davies A M
School of Biological and Medical Sciences, Bute Medical Buildings, University of St Andrews, St Andrews, Fife KY16 9AJ, Scotland, UK.
Curr Opin Neurobiol. 1997 Feb;7(1):110-8. doi: 10.1016/s0959-4388(97)80128-6.
In vitro and in vivo studies suggest that certain populations of neurons switch their survival requirements from one neurotrophin to another during an early stage in their development. Although there is good evidence for neurotrophin switching in sensory neurons, the evidence for switching in sympathetic neurons has become more controversial, as has the identity of the factors that regulate their responsiveness to particular neurotrophins.
体外和体内研究表明，某些神经元群体在其发育的早期阶段会将其生存需求从一种神经营养因子转变为另一种。虽然在感觉神经元中存在神经营养因子转换的充分证据，但在交感神经元中转换的证据却更具争议性，调节它们对特定神经营养因子反应性的因素的身份也是如此。
