Grau A J, Brandt T, Forsting M, Winter R, Hacke W
Neurology Department, University of Heidelberg, Germany.
Stroke. 1997 Feb;28(2):453-5. doi: 10.1161/01.str.28.2.453.
The pathogenesis of cervical artery dissection remains unknown. Infection-mediated damage of the arterial wall may be one contributing mechanism. We present three male patients with respiratory infection prior to cervical artery dissection.
Case 1: During an upper respiratory tract infection, a 49-year-old patient developed bilateral carotid and vertebral artery dissection with complete vessel restitution. Case 2: Within 3 years, a 40-year-old patient experienced two episodes of bilateral internal carotid artery dissection, both preceded by febrile upper respiratory tract infection. Case 3: A 52-year-old patient developed right-sided and, 2 years later, left-sided internal carotid artery dissection, each following upper respiratory tract infection.
Infection may be a trigger factor in the pathogenesis of cervical artery dissection.
颈动脉夹层的发病机制尚不清楚。感染介导的动脉壁损伤可能是一种促成机制。我们报告三例在颈动脉夹层发生前有呼吸道感染的男性患者。
病例1：一名49岁患者在上呼吸道感染期间发生双侧颈动脉和椎动脉夹层，血管完全恢复。病例2：一名40岁患者在3年内经历了两次双侧颈内动脉夹层，均在发热性上呼吸道感染之后。病例3：一名52岁患者先发生右侧颈内动脉夹层，2年后发生左侧颈内动脉夹层，每次均在上呼吸道感染之后。
感染可能是颈动脉夹层发病机制中的一个触发因素。
