Pantoni L, Poggesi L, Repice A, Inzitari D
Department of Neurological and Psychiatric Sciences, University of Florence, Italy.
Neurology. 1997 Feb;48(2):381-3. doi: 10.1212/wnl.48.2.381.
Tourette's syndrome (TS) is a disease characterized by multiple motor and vocal tics as well as behavioral abnormalities. The anatomic substrates of this syndrome are not defined. We report a 48-year-old man with TS in whom motor tics disappeared after the onset of a midbrain syndrome related to thiamine deficiency (Wernicke's encephalopathy). MRI study showed a lesion in the dorsal area of the midbrain. This case suggests that loops located in the midbrain tegmentum may influence the presence of motor tics in patients with TS.
图雷特综合征（TS）是一种以多种运动性和发声性抽动以及行为异常为特征的疾病。该综合征的解剖学基础尚不明确。我们报告一名48岁患有图雷特综合征的男性，其运动性抽动在与硫胺缺乏相关的中脑综合征（韦尼克脑病）发作后消失。磁共振成像（MRI）研究显示中脑背侧区域有一处病变。该病例提示，位于中脑被盖的环路可能影响图雷特综合征患者运动性抽动的出现。
